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AliasesHazard Evaluation Support System Integrated Platform
DescriptionHESS has two databases. One is a toxicity knowledge database, which contains information on repeated dose toxicity and toxicity mechanisms. The other is a metabolism knowledge database containing rat metabolism maps and information on absorption, distribution, metabolism and excretion (ADME) in rats and humans. HESS allows chemicals to be categorized on the basis of structural, physicochemical and mechanistic similarities and helps predict the repeated dose toxicity of untested chemicals by means of the category approach.(cited from original site)
Main Institutes of managementNational Institute of Technology and Evaluation (NITE)
Country of the InstituteJapan
URL of the sitehttps://www.nite.go.jp/chem/qsar/hess.html
Input exampleDownload the operation instructions movie (Japanese only, on Original site) http://www.safe.nite.go.jp/kasinn/qsar/hess_operating_manual_01.html
Keywordtoxicity knowledge information DB | metabolism knowledge information DB | hazard information for chemicals
Amount of the all data for download(Mbyte) | Method to obtain the all data.400 (softwea & database)|Download HESS and HESS DB from the URL shown in the message which verifies your registration.
External resources (databases) in building the product.None
Data typeChemical compound toxicity knowledge
Biological species in the main concernRat
Conditions of useAttribution&Noncommercial&No Derivative WorksUser registration
Frequency of updates (in last two years)1
Last date of updates (date of confirmation)2021/3/31 (2021/11/16)
Main IDs used in the productsNone
How to make a link to get access to each IDs.None
external databases to which this database/tool have linksNone
Published papers (PubMed IDs)None
Operational Statusavailable