Phosphorylation activity measurement-based pathway profiling database for drug-response

NamePhosphorylation activity measurement-based pathway profiling database for drug-response
DescriptionPhosprof (a phosphorylation activity measurement-based pathway profiling database for drug response) is a database that presents the cellular responses to representative drugs as significant pathways. It is based on the analysis of collected experimental data on the phosphorylation activities using protein arrays. The measurement of the phosphorylation activity allows the direct evaluation of the signal transduction activity and estimation of the pathways responsible for a particular cellular event. A comparison between the various approved drugs whose target phenotypes are already known can be helpful for further investigation of the drug functions and for drug development.
Main Institutes of managementNational Institute of Advanced Industrial Science and Technology (AIST)
Country of the InstituteJapan
URL of the site
Input exampleOn the top page, by selecting the check button of the cell line (MCF-7, K562), selecting the drug from the pull-down menu and pressing the submit button, the pathway containing the signature protein will be displayed.
KeywordPhosphorylation | Pathway | Signature protein | Drug
Amount of the all data for download(Mbyte) | Method to obtain the all data.0.0|none
External resources (databases) in building the product.None
Data typeProtein
Biological species in the main concernHuman
Conditions of useNone
Frequency of updates (in last two years)about once a year
Last date of updates (date of confirmation)2022/03/01(2022/05/23)
Main IDs used in the productsProtein ID
How to make a link to get access to each IDs.none
external databases to which this database/tool have linksNone
Published papers (PubMed IDs)PMID:35994309
Operational Statusavailable